Pentobarbital will reduce the level or outcome of ethotoin by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of. pentobarbital will decrease the level or outcome of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is a sensitive CYP3A4 substrate. Coadministration with solid or moderate CYP3A4 inducers is contraind... https://christians592lpu1.mybuzzblog.com/profile