Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130 kDa (Sap130). part of the chromatin modifying SIN3A/HDAC complex. as a gene contributing to the etiology of HLHS. https://www.truvisionhealthftp.com/